Accommodating covariates roc analysis sex dating in elkhorn wisconsin


07-Jun-2016 13:32

However, it has received little attention in the growing area of medical research devoted to the development of markers for disease diagnosis, screening, or prognosis, where classification accuracy, rather than association, is of primary interest.In this paper, the authors demonstrate the need for covariate adjustment in studies of classification accuracy, discuss methods for adjusting for covariates, and distinguish covariate adjustment from several other related, but fundamentally different, uses for covariates.We describe three ways of using covariate information.For factors that affect marker observations among controls, we present a method for covariate adjustment.

The concept of covariate adjustment is well established in therapeutic and etiologic studies.Classification accuracy is the ability of a marker or diagnostic test to discriminate between two groups of individuals, cases and controls, and is com- monly summarized by using the receiver operating characteristic (ROC) curve.



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